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It is very important that all Node Agents in a cell are up and running when you change security related settings, for example, when you enable global security or change user registry settings. Otherwise, synchronization with the Deployment Manager might fail due to inconsistent or missing security information when the Node Agent comes back up.
Other than this, a failure of a Node Agent does not have any impacts on an already set up and running secured environment because each appserver JVM hosts a security service. The security service uses the security settings held in the configuration repository to provide authentication and authorization functionality.
